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. 2014 Feb 28;25(1):16–27. doi: 10.1089/humc.2013.201

FIG. 2.

FIG. 2.

Hematology. Blood samples for hematology were collected from each NHP during the week before intracerebral injection of saline or M032. After injection on day 1, samples were collected on days 3, 10, 14, 31, and 91. Among the measurements carried out (A) white blood cells, (B) red blood cells, (C) hematocrit, (D) hemoglobin, (E) platelets, (F) reticulocytes, (G) neutrophils, (H) lymphocytes, (I) monocytes, (J) eosinophils, (K) basophils, and (L) large unstained (myeloperoxidase negative) cell counts are presented. Blood samples obtained from one male NHP before moribund euthanasia on day 16 are depicted as “X” in each plot. Error bars represent mean±SD. Preadministration to day 3; vehicle (n=6), M032 (n=12/dose). Days 4–31; vehicle (n=4), 1E6 M032 (n=8), 1E8 M032 (n=7 or 8; 1 animal euthanized moribund on day 16). Days 32–91; vehicle (n=2), 1E6 M032 (n=4), 1E8 M032 (n=3).