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Genes with somatic mutations and known roles in tumorigenesis
| Gene Symbol | Mutation Frequency |
|---|---|
| SMAD4 | 6/23 (26%) |
| JAK1 | 4/23 (17%) |
| BRAF | 3/23 (13%) |
| RB1 | 3/23 (13%) |
| TP53 | 3/23 (13%) |
| APC | 2/23 (9%) |
| ARID1A | 2/23 (9%) |
| GNAS | 2/23 (9%) |
| MLL3 | 2/23 (9%) |
| PTEN | 2/23 (9%) |
| ATM | 1/23 (4%) |
| BAP1 | 1/23 (4%) |
| BRCA2 | 1/23 (4%) |
| PALB2 | 1/23 (4%) |
| MEN1 | 1/23 (4%) |
| RNF43 | 1/23 (4%) |
