Table 1.

Characteristics of the study population (n = 317)

	TP group n = 126 (40%)	TP + IAT group n = 191 (60%)	P-value
Age, years, median (range)	54 (18–78)	40 (18–70)	< 0.0001
Male, n (%)	51 (40%)	48 (25%)	0.006
Active tobacco use, n (%)	42 (33%)	60 (31%)	0.720
Alcohol abuse, n (%)	3 (2%)	0	0.059
Weight loss of > 10% in 6 months, n (%)	15 (12%)	11 (6%)	0.051
Albumin, g/dl, median (range)	3.9 (1.5–5.1)	4.1 (1.9–5.4)	0.011
Comorbidities, n (%)
Chronic pulmonary disease	5 (4%)	3 (2%)	0.183
Hypertension	59 (47%)	25 (13%)	< 0.001
Diabetes	42 (33%)	18 (9%)	< 0.001
Coronary artery disease	13 (10%)	4 (2%)	0.002
ASA class of ≥ 3, n (%)	93 (74%)	121 (63%)	0.052
Diagnosis, n (%)
Chronic pancreatitis	73 (58%)	171 (90%)	< 0.001
Acute pancreatitis	13 (10%)	14 (7%)
Benign neoplasm	40 (32%)	6 (3%)	< 0.001
Concurrent procedure, n (%)
Splenectomy	55 (44%)	146 (76%)	< 0.001
Gastrectomy	10 (8%)	0	< 0.001
Lymphadenectomy	3 (2%)	2 (1%)	0.351
Operative time, min, median (range)	310 (75–1140)	530 (370–1007)	< 0.0001

TP, total pancreatectomy; IAT, islet cell auto-transplantation; ASA, American Society of Anesthesiologists.