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. 2014 May 30;592(Pt 11):2375–2379. doi: 10.1113/jphysiol.2014.272138

Figure 1. Diagram of cross-species nuclear transfer (NT).

Figure 1

Left: development of a regularly fertilized embryo of species A; right: development of a cross-species NT embryo with a nucleus from species A combined with an enucleated egg from species B. The egg cytoplasm of species A and species B contains different types of maternal factors, such as RNAs, proteins and lipids, etc. After nuclear transfer, the reconstructed embryo that contains the nucleus of species A and the cytoplasm of species B may develop into an animal that does not fully resemble species A.