TABLE 1.
Total N = 117 (%) |
FALP N = 22 (%) |
YCU N = 19 (%) |
MSKCC N = 76 (%) |
p | |
---|---|---|---|---|---|
Gender | 0.9 | ||||
Female | 75 (64.1) | 15 (68.2) | 12 (63.2) | 48 (63.2) | |
Male | 42 (35.9) | 7 (31.8) | 7 (36.8) | 28 (36.8) | |
Age (years) | 0.056 | ||||
Median (range) | 65 (28–91) | 60 (41–91) | 63 (48–85) | 69 (28–90) | |
Mean ± SD | 65.4 ± 11.4 | 60.3 ± 12.3 | 65.8 ± 10.2 | 66.8 ± 11.1 | |
Race | <0.0001 | ||||
Caucasian | 58 (49.6) | 0 | 0 | 58 (76.3) | |
Hispanic | 26 (22.2) | 21 (95.5) | 0 | 5 (6.6) | |
Asian-Japanese | 19 (16.2) | 0 | 19 (100) | 0 | |
African-American | 3 (2.6) | 0 | 0 | 3 (3.9) | |
Pacific Islander | 2 (1.7) | 0 | 0 | 2 (2.6) | |
Asian-American | 3 (2.6) | 0 | 0 | 3 (3.9) | |
Indian | 1 (0.9) | 0 | 0 | 1 (1.3) | |
Native American | 1 (0.9) | 1 (4.5) | 0 | 0 | |
Unknown | 4 (3.4) | 0 | 0 | 4 (5.3) | |
Gallstones | <0.0001 | ||||
Yes | 94 (80.3) | 22 (100) | 9 (47.4) | 63 (82.9) | |
No | 23 (19.7) | 0 | 10 (52.6) | 13 (17.1) | |
Incidental | <0.0001 | ||||
Yes | 46 (39.3) | 12 (54.5) | 0 | 34 (44.7) | |
No | 71 (60.7) | 10 (45.5) | 19 (100) | 42 (55.3) | |
Curative resection | 0.027 | ||||
Yes | 71 (60.7) | 8 (36.4) | 14 (73.7) | 49 (64.5) | |
No | 46 (39.3) | 14 (63.6) | 5 (26.3) | 27 (35.5) | |
Main procedure | 0.002 | ||||
Segmentectomy 4B/5 | 49 (41.9) | 7 (31.8) | 9 (47.4) | 33 (43.4) | |
Segmentectomy 4B/5 + PDD | 4 (3.4) | 1 (4.5) | 2 (10.5) | 1 (1.3) | |
Extended hepatectomy | 28 (23.9) | 0 | 6 (31.6) | 22 (28.9) | |
Cholecystectomy (noncurative) | 27 (23.1) | 12 (54.5) | 0 | 15 (19.7) | |
Cholecystectomy (curative) | 5 (4.3) | 1 (4.5) | 2 (10.5) | 2 (2.6) | |
Nonresection | 4 (3.4) | 1 (4.5) | 0 | 3 (3.9) | |
Hepatic resection | <0.0001 | ||||
Yes | 81 (69.2) | 8 (36.4) | 17 (89.5) | 56 (73.7) | |
No | 36 (30.8) | 14 (63.6) | 2 (10.5) | 20 (26.3) | |
Bile duct resection | <0.0001 | ||||
Yes | 56 (47.9) | 3 (13.6) | 14 (73.7) | 39 (51.3) | |
No | 61 (52.1) | 19 (86.4) | 5 (26.3) | 37 (48.7) | |
Adjacent organ resection | 0.1 | ||||
Yes | 15 (12.8) | 0 | 3 (15.8) | 12 (15.8) | |
No | 102 (87.2) | 22 (100) | 16 (84.2) | 64 (84.2) | |
Adjuvant therapy | 0.1 | ||||
Yes | 53 (45.3) | 6 (27.3) | 11 (57.9) | 36 (47.4) | |
No | 64 (54.7) | 16 (72.7) | 8 (42.1) | 40 (52.6) | |
T stage | 0.001 | ||||
1 | 5 (4.3) | 1 (4.5) | 1 (5.3) | 3 (3.9) | |
2 | 41 (35) | 14 (63.6) | 5 (26.3) | 22 (28.9) | |
3 | 63 (53.8) | 6 (27.3) | 9 (47.4) | 48 (63.2) | |
4 | 5 (4.3) | 0 | 4 (21.1) | 1 (1.3) | |
Unknown | 3 (2.6) | 1 (4.5) | 0 | 2 (2.6) | |
Histology | 0.3 | ||||
Adenocarcinoma | 106 (90.6) | 21 (95.5) | 17 (89.5) | 68 (89.5) | |
Adenosquamous | 6 (5.1) | 1 (4.5) | 0 | 5 (6.6) | |
Squamous | 2 (1.7) | 0 | 0 | 2 (2.6) | |
Neuroendocrine | 2 (1.7) | 0 | 1 (5.3) | 1 (1.3) | |
Undifferentiated | 1 (0.9) | 0 | 1 (5.3) | 0 | |
Differentiation | <0.0001 | ||||
Well | 16 (13.7) | 1 (4.5) | 10 (52.6) | 5 (6.6) | |
Moderate | 61 (52.1) | 15 (68.2) | 5 (26.3) | 41 (53.9) | |
Poor | 40 (34.2) | 6 (27.3) | 4 (21.1) | 30 (39.5) | |
Lymphovascular invasion (n = 88) | 0.2 | ||||
No | 42 (47.7) | 5 (45.5) | 6 (31.6) | 31 (53.4) | |
Yes | 46 (52.3) | 6 (54.5) | 13 (68.4) | 27 (46.6) | |
Perineural invasion (n = 81) | 0.8 | ||||
No | 30 (37) | 4 (40) | 8 (42.1) | 18 (34.6) | |
Yes | 51 (63) | 6 (60.0) | 11 (57.9) | 34 (65.4) | |
Lymph node stage | 0.03 | ||||
Negative | 39 (33.3) | 4 (18.2) | 4 (21.1) | 31 (40.8) | |
Positive | 64 (54.7) | 12 (54.5) | 14 (73.7) | 38 (50) | |
Unknown | 14 (12) | 6 (27.3) | 1 (5.3) | 7 (9.2) | |
Lymph nodes resected | <0.0001 | ||||
Median (range) | 3.5 (0–55) | 4 (0–13) | 13 (0–55) | 3 (0–17) | |
Mean ± SD | 6.6 ± 9.5 | 4.6 ±4 | 19 ± 17 | 3.9 ± 3.7 | |
Positive lymph nodes | 0.019 | ||||
Median (range) | 1 (1–43) | 2 (1–7) | 2 (1–43) | 1 (1–6) | |
Mean ± SD | 1.6 ± 4.2 | 1.3 ± 1.8 | 4 ± 9.6 | 1 ± 1.5 | |
TNM stage | 0.02 | ||||
1 | 3 (2.6) | 0 | 1 (5.3) | 2 (2.6) | |
2 | 10 (8.5) | 4 (18.2) | 2 (10.5) | 4 (5.3) | |
3a | 21 (17.9) | 0 | 1 (5.3) | 20 (26.3) | |
3b | 37 (31.6) | 7 (31.8) | 7 (36.8) | 23 (30.3) | |
4a | 3 (2.6) | 0 | 2 (10.5) | 1 (1.3) | |
4b | 43 (36.8) | 11 (50) | 6 (31.6) | 26 (34.2) |
PDD pancreaticoduodenectomy