Skip to main content
. 2014 Jun 6;9(6):e98670. doi: 10.1371/journal.pone.0098670

Figure 5. p66shc mediates CRIF1 deficiency-induced adhesion of monocytes to endothelial cells (HUVECs).

Figure 5

(A) CRIF1 deficiency induced monocyte adhesion to HUVECs. HUVECs were transfected with Crif1 siRNA for 48 h. Representative photomicrographs of U937 cells adherent to HUVECs (A, upper panel) and quantification of adherent cells (A, lower panel) are shown. (B) p66shc mediates CRIF1 deficiency-induced adhesion of monocytes to HUVECs. HUVECs infected with Adp66shcRNAi or AdLacZ were transfected with Crif1 siRNA for 48 h and incubated with U937 cells for 30 min. Representative photomicrographs of U937 cells adherent to HUVECs (B, upper panel) and quantification of adherent cells (B, lower panel) are shown. Data represent means ± SEM of three independent experiments, *P<0.05 compared with the control.