Table 3. Univariate and multivariate analysis of predictive factors for the presence of concomitant acute kidney injury^a.

	Univariate Analysis		Multivariate Analysis
Variables	OR (95% CI)	p value	OR (95% CI)	p value
Age	1.05 (1.003–1.09)	0.034	1.03 (0.98–1.08)	0.26
Male gender	2.72 (0.86–8.59)	0.09	2.72 (0.74–10.03)	0.13
Comorbidity
Diabetes mellitus	1.28 (0.54–3.03)	0.58
Obstructive airway disease	0.89 (0.36–2.19)	0.80
Interstitial lung disease	0.28 (0.07–1.12)	0.07	0.26 (0.06–1.21)	0.09
Chronic renal insufficiency	1.40 (0.50–3.95)	0.52
Congestive heart failure	1.41 (0.43–4.62)	0.57
Estradiol (E2) >40 pg/mL	5.96 (2.56–13.91)	<0.001	4.73 (1.80–12.44)	0.002
Progesterone >1.13 ng/mL	2.73 (1.24–6.02)	0.013	1.33 (0.50–3.50)	0.57
Testosterone >4.4 ng/mL	1.04 (0.49–2.23)	0.92

^aPneumonia-related septic shock patients enrolled for analysis.

OR, odds ratio; CI, confidence interval.