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. 2014 Jun 6;9(6):e99008. doi: 10.1371/journal.pone.0099008

Table 1. Patient characteristics.

Panel I (n = 14) Panel II (n = 51) P*
Median Age (range), years 65.2 (45.8–78.3) 63.8 (38.8–80.4) 0.380
Gender, No. (%)
Female 6 (42.9) 16 (31.4) 0.527
Male 8 (57.1) 35 (68.6)
T stage primary tumor, No. (%)
T0 0 (0) 1 (2.0) 0.521
T1 0 (0) 3 (5.9)
T2 5 (35.7) 7 (13.7)
T3 8 (57.1) 30 (58.8)
T4 1 (7.1) 7 (13.7)
n.a. 0 (0) 3 (5.9)
N stage primary tumor, No. (%)
node negative 5 (35.7) 19 (37.3) 0.794
node positive 9 (64.3) 29 (56.9)
n.a. 0 (0) 3 (5.9)
M stage primary tumor, No. (%)
M0 14 (100) 21 (41.2) n.a.
M1 n.a. 29 (56.9)
n.a. 0 (0) 1 (2.0)
Median number of metastases (range) 2 (1–10) 2 (1–10) 0.491
Largest median diameter, cm (range) 2.6 (0.8–7.0) 2.0 (0.3–13.0) 0.345
Median % vital tumor cells (range) n.a. 25 (0–90) n.a.
Median disease free interval, months 25.1 (7.9–117.2) 18.0 (0–116.5) 0.166
Type of cytotoxic chemotherapy, No. (%) within 6 months of liver resection
fluoropyrimidine+oxaliplatin n.a. 46 (90.2) n.a.
fluoropyrimidine+irinotecan n.a. 5 (9.8)
Regimens containing bevacizumab n.a. 51 (100)

*Wilcoxon's rank sum test was used for continuous variables, Chi-square test for ordinal variables.

According to the inclusion criteria for panel I, all patients were M0 at the time of diagnosis of primary tumor.