Table 1. Patient characteristics.
Panel I (n = 14) | Panel II (n = 51) | P* | |
Median Age (range), years | 65.2 (45.8–78.3) | 63.8 (38.8–80.4) | 0.380 |
Gender, No. (%) | |||
Female | 6 (42.9) | 16 (31.4) | 0.527 |
Male | 8 (57.1) | 35 (68.6) | |
T stage primary tumor, No. (%) | |||
T0 | 0 (0) | 1 (2.0) | 0.521 |
T1 | 0 (0) | 3 (5.9) | |
T2 | 5 (35.7) | 7 (13.7) | |
T3 | 8 (57.1) | 30 (58.8) | |
T4 | 1 (7.1) | 7 (13.7) | |
n.a. | 0 (0) | 3 (5.9) | |
N stage primary tumor, No. (%) | |||
node negative | 5 (35.7) | 19 (37.3) | 0.794 |
node positive | 9 (64.3) | 29 (56.9) | |
n.a. | 0 (0) | 3 (5.9) | |
M stage primary tumor, No. (%) | |||
M0 | 14 (100)‡ | 21 (41.2) | n.a. |
M1 | n.a. | 29 (56.9) | |
n.a. | 0 (0) | 1 (2.0) | |
Median number of metastases (range) | 2 (1–10) | 2 (1–10) | 0.491 |
Largest median diameter, cm (range) | 2.6 (0.8–7.0) | 2.0 (0.3–13.0) | 0.345 |
Median % vital tumor cells (range) | n.a. | 25 (0–90) | n.a. |
Median disease free interval, months | 25.1 (7.9–117.2) | 18.0 (0–116.5) | 0.166 |
Type of cytotoxic chemotherapy, No. (%) within 6 months of liver resection | |||
fluoropyrimidine+oxaliplatin | n.a. | 46 (90.2) | n.a. |
fluoropyrimidine+irinotecan | n.a. | 5 (9.8) | |
Regimens containing bevacizumab | n.a. | 51 (100) |
*Wilcoxon's rank sum test was used for continuous variables, Chi-square test for ordinal variables.
According to the inclusion criteria for panel I, all patients were M0 at the time of diagnosis of primary tumor.