Table 5. Multivariate survival analysis (Cox' proportional hazards regression model) of the vascular invasion signature score.
Data set | Variables | HR1 | 95% CI2 | P-value3 |
Disease specific survival | ||||
GSE14564 | Vascular invasion score | 2.7 | 1.2–6.1 | 0.019 |
Tumor grade | 1.9 | 1.0–3.9 | 0.068 | |
Overall survival | ||||
GSE206855 | Vascular invasion score | 2.0 | 1.3–3.2 | 0.002 |
Recurrence free survival | ||||
GSE14564 | Vascular invasion score | 1.9 | 1.0–3.9 | 0.063 |
Tumor grade | 1.8 | 1.1–3.1 | 0.032 | |
GSE206855 | Vascular invasion score | 1.8 | 1.2–2.9 | 0.010 |
Adjusted Hazard ratio,
95% confidence interval,
Lratio test, Final model after inclusion of: 4Vascular invasion score, histologic grade and molecular subtype or 5Vascular invasion score and molecular subtype.
Data presented for disease specific survival, overall survival and recurrence free survival.