Table 6. Association between the 18-gene signature score and response to treatment (mean signature score is given).

	Response
GSE22358 (N = 154)	Neoadjuvant chemotherapy			Chemotherapy + trastuzumab
	npCR1/pCR2	NR3/PR4	p-value5	npCR/pCR	NR/PR	p-value5
	3.25	−1.15	0.017	3.17	−0.12	0.089
GSE20271 (N = 178)	FAC treated			T/FAC treated
	pCR	RD6	p-value	pCR	RD	p-value
	0.10	0.21	NS	−0.26	−0.02	NS
GSE 20194 (N = 230)	Neoadjuvant chemotherapy
	pCR	RD	p-value
	2.18	−0.55	<0.001

¹Near-complete pathologic response,

²Pathologic complete response,

³No response,

⁴Partial respons,

⁵Mann-Whitney U test,

⁶Residual disease.