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. 2014 Jun 6;9(6):e99118. doi: 10.1371/journal.pone.0099118

Figure 2. PMCA isoforms expression pattern versus transcriptional control by NFAT in PC12 cells.

Figure 2

Expression of genes encoding PMCA isoforms: Atp21b1 (PMCA1), Atp21b2 (PMCA2), Atp21b3 (PMCA3), Atp21b4a (PMCA4a), Atp21b4b (PMCA4b) was determined by qPCR for PC12 cells non-treated (A), and treated with NFAT inhibitor (1 µM 11R-VIVIT) (B). Bars represent mean values ± SEM. Wilcoxon test was used for ΔCt from qPCR data (n = 3) for comparison between control cells (standardized to y = 0) and PMCA2- or PMCA3-deficient cells non-treated with 11R-VIVIT (n = 3). Two-way ANOVA test was used for comparison between non-treated and 11R-VIVIT treated cells. *P≤0.05, **P≤0.01.