Table 2. Laboratory findings and pulmonary function tests in myositis-associated ILD.
| Total | PM-ILD | DM-ILD | CADM-ILD | P<0.05 | |
| Laboratory findings | |||||
| WBC, mm−3 | 6815 (5253, 9693) | 8930 (5993, 12625) | 7700 (5350, 13980) | 5720 (4700, 7300) | †, ‡ |
| CRP, mg/dL | 0.77 (0.16, 2.6) | 0.77 (0.2, 3.2) | 1.6 (0.3, 3.5) | 0.28 (0.1, 1.4) | ‡ |
| CPK, IU/L | 332 (117, 1166) | 1862 (842, 4915) | 582 (250, 956) | 109 (71, 163) | *, †, ‡ |
| Aldolase, IU/L | 12.2 (6.3, 24.6) | 26.3(12.4, 49.4) | 12.8 (7.9, 26.8) | 7.1 (4.3, 12.0) | *, †, ‡ |
| LDH, IU/L | 393 (287, 598) | 630 (430, 882) | 399 (301, 566) | 307 (217, 417) | *, †, ‡ |
| IgG, mg/dL | 1667 (1365, 2027) | 1869 (1463, 2104) | 1473 (1243, 2020) | 1669 (1518, 1974) | NS |
| KL-6, U/mL | 1115 (728.5,1477.5) | 1747 (760, 3196) | 1180 (767, 1470) | 960 (652, 1367) | † |
| Positive ANA, % | 32.5 | 23.3 | 41.5 | 30.2 | NS |
| Positive Jo-1, % | 19.3 | 31.0 | 15.4 | 17.1 | NS |
| PaO2, Torr | 71.7 (63.4, 80.7) | 75.0 (64.3, 86.4) | 69.0 (63.0, 80.6) | 72.2 (66.2, 80.7) | NS |
| PaCO2, Torr | 38 (35.6, 40.7) | 39.4 (35.9, 42.7) | 37.1 (34.8, 40.0) | 38.7 (35.1, 40.7) | NS |
| Pulmonary function tests | |||||
| FVC, % predicted | 66.3 (56.9, 82.0) | 71.1 (57.7, 90.0) | 65.4 (57.0, 77.2) | 66.4 (54.8, 83.6) | NS |
| FEV1/FVC, % | 83.3 (76.1, 88.3) | 85.5 (76.8, 89.6) | 83.3 (77.3, 86.2) | 82.6 (75.5, 90.4) | NS |
| %DLCO, % | 65.5 (51.7, 82.9) | 78.5 (48.1, 89.2) | 65.1 (51.0, 81.3) | 64.3 (51.3, 84.7) | NS |
*; PM vs DM, †; PM vs CADM, ‡; DM vs CADM, NS; not significant in Kruskal-Wallis test.
Data are presented as the medians (interquartile ranges).
ILD: interstitial lung disease; WBC: white blood cell count; CRP: C-reactive protein; CPK: creatine phosphokinase; LDH: lactic dehydrogenase; IgG: immunoglobulin G; ANA: antinuclear antibody; FVC: forced vital capacity; FEV1: forced expiratory volume; DLCO: diffusing capacity of the lung for carbon monoxide.