Figure 2. Differences in weight-loss between CLOCK genotypes and emotion eating classification as assessed by EEQ.

By dichotomizing the participants into ‘emotional eaters’ and ‘non-emotional eaters’, we found significantly different effects across genotypes at this locus (P for interaction  = 0.017). Among minor C allele carriers, ‘emotional eaters’ lost significantly less weight than ‘non-emotional eaters’ (P = 0.0049). However, no significant differences were identified between ‘emotional eaters’ and ‘non-emotional eaters’ for total weight-loss among noncarriers (P = 0.454). Data are presented as mean ± s.e.m. We used (*) to indicate significant differences between emotional eating groups with the same genotype (P<0.050).