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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Nat Med. 2014 May 4;20(6):670–675. doi: 10.1038/nm.3544

Figure 3.

Figure 3

Reduced decorin binding to type I collagen of Crtap−/− mice. (a) Quantitative RTPCR of calvarial bone of P3 mice for the small leucine-rich proteoglycans decorin (Dcn), biglycan (Bgn), and asporin (Aspn) in WT and Crtap−/− mice. Results given as fold change of the mean of WT group±SD, n=5 per group. NS, not significant. (b) Surface plasmon resonance analysis measuring the binding of recombinant decorin core protein to type I collagen of WT and Crtap−/− mice. Three technical replicates at each of the indicated concentrations of decorin were performed in two independent biological replicates (◆ replicate 1, ▲ replicate 2). Results are shown as the percentage of the mean of WT (bars indicate mean per group).