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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Curr Osteoporos Rep. 2014 Mar;12(1):48–54. doi: 10.1007/s11914-014-0187-2

Figure 1. Strategies for healing osteoporotic and cancer-induced bone disease (CIBD) fractures.

Figure 1

(A) Pre-operative radiograph of a hip fracture (arrow) in an 84 year-old female patient. (B) Postoperative radiograph showing fixation of the fracture with an intra-medullary hip lag screw coated with hydroxyapatite (HA). (C) Stabilization and osseointegration of implants using osteoconductive bone grafts. (D) Re-establishment of normal bone healing by local delivery of biologics (e.g., mesenchymal stem cells, rhBMP-2, or platelet-rich plasma (shown in red)) from bone grafts and scaffolds. Adapted from A Moroni et al. Can we improve fixation and outcomes? Use of bone substitutes. J Orthop Trauma 23:422–425, 2009 [29].