Figure 1.
Comparison of technical and biological replicates. A: The technical replicate was generated from spinach medium by splitting the libraries before PCR of SOLiD sequencing. The mapped counts were normalized and are given in fragments/gene according to Haas et al. (51). The correlation coefficient R 2 is virtually 1.0. B: Biological replicates for LB medium are shown. They were sequenced on two different platforms, the SOLiD 4.0 system and the Illumina MiSeq sequencer, to exclude technical artifacts of one platform. The correlation coefficient R 2 is 0.72.