Fig. 3.

BTS treatment reduces hepatic inflammation and oxidative stress. a The extent of hepatic inflammation was markedly attenuated with BTS: hepatocyte ballooning and Mallory–Denk bodies in the livers of GTG + HF fed mice were absent in BTS treatment livers. Filled arrow ballooning hepatocyte, arrow Mallory–Denk body. b Oxidative stress and TNF-α expression: BTS reduced hepatic oxidative stress as shown by reduction of numbers of nuclei stained positive for 8-OHdG in GTG + HF mice. BTS similarly reduced hepatic TNF-α mRNA expression. Triple asterisk p < 0.001, asterisk p < 0.01 vs GTG + HF, Triple plus symbol p < 0.001 vs 2 %BTS, n = 6