Tabel 1.

Studies that have investigated the neuroprotective effects of natural polyphenols using experimental models of SCI

Polyphenols	Model of SCI	Effects	Reference
Green tea	Trauma	Bax, Bcl-2 MDA MPO, demyelination TNF-α, IL-1β, iNOS, COX-2, PARP, nitrotyrosine	[27, 28, 30] [28, 30] [29] [29, 30]
Olive oil	Trauma	Lipid peroxidation Bax, Bcl-2, GSH TNF-α, IL-1β, iNOS, COX-2, PARP, nitrotyrosine FAS, Caspase-3, GDNF, IKK-α, NF-κβ P65	[61, 63, 64] [61] [62, 64] [64]
Resveratrol	Trauma I/R	Edema, MDA MDA, GSH, xanthine oxidase TNF-α, IL-1β, IL-10, MPO, Oxidative stress, NO Oxidative stress, neutrophil infiltration	[92] [93] [94] [95] [96]
Turmeric	Trauma Hemisection	Lipid peroxidation Glutathione peroxidase Superoxidase dismutase, catalase Astrocyte reaction Astrocyte reaction	[114, 116, 117] [109] [114, 116] [118, 119] [113]

Malondialdehyde (MDA), Myeloperoxidase (MPO), Isoform of nitric oxide synthase (iNOS), Poly (ADP-ribose) polymerase (PARP), Glial cell-derived neurotrophic factor (GDNF), Glutathione (GSH), Ischemia-reperfusion (I/R)