Table-III.

ERCC1, BRCA1, RRM1 and RRM2 mRNA expression and overall survival of advanced NSCLC

Gene	Death	%	Alive	%	Overall Survival Median (month)	Log-rank	OS
	N=113		N=95				HR(95%CI)	P value
High ERCC1	66	58.4	38	40.0	16.05		1.0(Ref.)
Low ERCC1	47	41.6	57	60.0	21.32	0.02	0.43(0.27-0.89)	0.008
High BRCA1	70	61.9	34	35.8	14.75		1.0(Ref.)
Low BRCA1	43	38.1	61	64.2	22.61	0.004	0.37(0.22-0.66)	<0.001
High RRM1	62	54.9	42	44.2	17.25		1.0(Ref.)
Low RRM1	51	45.1	53	55.8	19.65	0.17	0.65(0.39-1.23)	0.58
High RRM2	58	51.3	46	48.4	18.6		1.0(Ref.)
Low RRM2	55	48.7	49	51.6	20.7	0.75	0.89(0.50-1.59)	0.68