Figure 4.

Resveratrol treatment attenuates TAC-induced cardiac fibrosis. The top (interstitial fibrosis) and middle panels (perivascular fibrosis) show representative tissue sections (LV, day 28) from sham, TAC, and TAC + resveratrol mice that were stained for collagen and quantified (bottom panels) as described in the Materials and Methods section. Values are expressed as the mean ± SD. *P < 0.05 was considered statistically significant.