Figure 8.

Resveratrol treatment alters pathways that regulate apoptosis, hypoxia, and oxidative stress. (A) Representative composite Western blots of cleaved caspase 3, and HIF1α from LV protein extracts of sham surgery, TAC, and TAC + resveratrol treatment (28 day). (B) Quantification of cleaved caspase 3. (C) HIF1α protein levels. (D) SOD activity. (E) Glutathione content. All values were normalized to β-actin levels. Values are represented as mean ± SD. *P < 0.05 was considered statistically significant.