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. 2014 May 24;9(1):261. doi: 10.1186/1556-276X-9-261

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Copyright © 2014 Kura et al.; licensee Springer.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Microscopic appearance of the kidney stained with H & E. Microarchitecture of kidney tissues stained with H & E and viewed at ×10 magnification in rats 4 weeks post-exposure to different concentrations of ZALH (A), ZALL (B), ZAH (C), ZAL (D) and vehicle control (E). G, glomerular; T, tubule. Micrographs (A) and (C) (encircled areas) show some leukocyte infiltrations which are eosinophilic glomerular due to inflammation likely caused by high dose of the nanocomposite delivery system. The two areas from (A) and (C) were viewed under higher magnification and they are presented in Figure 7.