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. Author manuscript; available in PMC: 2015 Jun 2.
Published in final edited form as: Annu Rev Biochem. 2014 Mar 5;83:441–466. doi: 10.1146/annurev-biochem-060713-035524

Figure 4.

Figure 4

Example of an RNA chaperone. The bound chaperone destabilizes the neighboring RNA helix, promoting melting dynamics, and then binds the exposed nucleotides. The other strand is released and can interact with other RNAs, and the remainder of the helix is also destabilized.