. Author manuscript; available in PMC: 2015 Jul 1.

Published in final edited form as: Addiction. 2014 Jul;109(7):1119–1127. doi: 10.1111/add.12537

Table 4b.

Hazard ratios (HR) with 95% confidence intervals (95% CI) of future drug use disorder (DUD) in a sibling-pair analysis, they being discordant for unexpected adverse childhood experience (UACE) and DUD (N = 5772 pairs)

	Model S1 HR (95 % CI)	Model S2^* HR (95 % CI)
UACE (P)	1.46 (1.34; 1.60)	1.46 (1.34; 1.59)
UACE (P) (siblings 1–5 years apart)	1.36 (1.23; 1.49)	1.36 (1.23; 1.49)
UACE (P) (siblings > 5 years apart)	2.04 (1.66; 2.51)	1.92 (1.55; 2.38)

Adjusted for parental divorce

Parent (P)