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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: J Cardiovasc Pharmacol. 2014 Jun;63(6):533–543. doi: 10.1097/FJC.0000000000000078

Figure 6. Average inhibition of PP2 on surface expression and tyrosine phosphorylation of HCN4 in sinus node myocytes.

Figure 6

Fluorescence signals for HCN4 surface fluorescence and tyrosine phosphorylation normalized to cell are represented in arbitrary unit (AU). ISO’s effects are shown in light grey bars. PP2’s effects are shown in open bars. PP2’s effects in the presence of ISO are shown in dark grey bars. The average results were from fluorescence analysis in 20 myocytes. * indicates statistically significant difference on surface expression compared to untreated myocytes. # indicates statistically significant difference on tyrosine phosphorylation state compared to untreated myocytes.