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Effects of PP2 and ISO on HCN4 gating properties
| Vth(mV) | V1/2(mV) | τ-act (−120mV) (ms) | |
|---|---|---|---|
| Control | −66.7±3.6(n=15) | −87.2±3.5(n=10) | 2439±110(n=10) |
| PP2* | −78.3±2.8(n=9) | −93.5±2.9(n=7) | 4075±305(n=7) |
| ISO | −59.1±4.4(n=7) | −82.3±2.3(n=7) | 1356±127(n=7) |
| PP2*+ISO | −83.3±3.3(n=6) | −100.9±2.3(n=6) | 3135±173(n=6) |
PP3 did not have the effects of PP2 shown in the table.
