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Sprouty/Tbxl interactions during thymus development
| Spry1 | Spry2 | Tbx1 | n | Normal | Hypoplasia | Hypoplasia with ectopia | Aplasia | TOTAL |
|---|---|---|---|---|---|---|---|---|
| +/+ | +/+ | +/− | 35 | 28 | 7 | 0 | 0 | 7 |
| +/− | +/− | +/+ | 23 | 23 | 0 | 0 | 0 | 0 |
| +/− | 35 | 32 | 3 | 0 | 0 | 3 | ||
| −/− | +/− | +/+ | 20 | 18 | 1 | 1 | 0 | 2 |
| +/− | 35 | 30 | 2 | 1 | 2 | 5 | ||
| +/− | −/− | +/+ | 13 | 13 | 0 | 0 | 0 | 0 |
| +/− | 24 | 9 | 9* | 1 | 5 | 15** | ||
| −/− | −/− | +/+ | 7 | 0 | 0 | 7 | 0 | 7 |
| +/− | 16 | 0 | 5 | 0 | 11*^ | 16 |
Shaded cells indicate significant difference between Tbx1+/+ and Tbx1+/− embryos:
p=0.015
p=0.0002
p=0.005
