Table 1.

Identification of anatomy, hemispheric location (L/R), coordinates (x,y,z) in MNI space (mm), analysis of covariance results statistics, and effect size for the difference within clusters in which relapsers showed significantly higher FC than abstainers within the (A) NAcc FC map and (B) sgACC FC map at Time 1 (~5 weeks of abstinence).

Anatomy of regions within identified clusters	L/R	x	y	z	Higher FC in REL at Time 1 (REL>ABS)			Larger reduction of FC in REL across time (Time 2 -Time 1) (REL>ABS)
					F	p	Effect size partial η2	F	p	Effect size partial η2
(A) NAcc network differences
Frontopolar prefrontal cortex (FP-PFC)	L	−30	62	0	6.3	0.02	2.8	5.8	0.04	3.7
Posterior cingulate cortex (PCG)	L/R	−2	−76	20	5.4	0.03	2.5	9.3	0.01	4.8
(B) SgACC network differences
Frontopolar prefrontal cortex (FP-PFC)	L	−24	62	−4	7.8	0.01	3.3	7.0	0.02	4.1