Figure 2. The abnormal T cell distribution in CVID-Mgat2^ΔM/ΔM mice is maintained with age and independent of changes in T cell surface glycosylation.

A) Representative analysis of blood CD4⁺ T cell phenotype from the same naïve Mgat2^ΔM/ΔM or CVID-Mgat2^ΔM/ΔM mouse at 12 and 27 weeks of age. Comparison between B) T cell (CD3⁺) and C) neutrophil (Gr1⁺CD11b⁺) cell glycosylation profiles from Mgat2^wt/wt, naïve Mgat2^ΔM/ΔM, and CVID-Mgat2^ΔM/ΔM mice using flow cytometry and fluorescently labeled PHA-L lectin. *p<0.05