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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: J Immunol. 2014 May 16;192(12):5749–5760. doi: 10.4049/jimmunol.1303260

Table III.

Classification of T/NK-cell and DC potential in CD34+CD7+ and CD34+CD10+clones

In vivo CD34+CD7+ and CD34+CD10+ clones Number of clones producing DC
cDC and pDC cDC pDC No DC Total
T and NK 0 4 (4)a 0 15 (3) 19 (7)
T 0 4 (4) 0 10 (0) 14 (4)
NK 2 (1) 1 (1) 0 79 (17) 82 (19)

T/NK subtotal 2 (1) 9 (9) 0 104 (20) 115 (30)
CD7+CD5CD56 0 3(3) 0 5 (1) 8 (4)
Myeloid w/o CD7+ cells 0 6 0 172 178
DC alone 0 14 0 - 14

Total 2 32 0 281 315

CD34+Lin CD7+ or CD34+Lin CD10+ were sorted from 5 donors at single cell per well and cultured with OP9-DL1 cells for 4 to 5 weeks. The presence of T/NK/DC progenies was analyzed and classified, as noted in Table II. The difference in distribution of total DC-producer clones were significant by chi-square test (Yates' correction) (P = 0.002), based on the number of clones between the total T lineage-(T/NK dual lineage- plus T single lineage-phenotypes) and NK single lineage-phenotype (T: 8 producer clones vs 25 non-producer clones, NK: 3 producer clones vs 79 non-producer clones).

a

Number of clones accompanying monocyte and/or granulocyte progenies in parentheses.