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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: J Immunol. 2014 Apr 30;192(12):5839–5851. doi: 10.4049/jimmunol.1302729

Figure 3. Enhanced CD8+ T-cell responses in memTNFΔ1–9, K11E KI and TNF−/− mice following influenza infection.

Figure 3

WT, memTNFΔ1–9, K11E KI, and TNF−/− mice were infected with a sub-lethal dose of influenza virus and cells were harvested from the airways, lung, and MLN on day 8 post-infection. Total number of viable cells recovered from (A) BAL, (B) lung, and (C) MLN. Total number of CD8+ T cells from (D) BAL, (E) lung, and (F) MLN. Total number of NP366–374-specific CD8+ T cells from (G) BAL, (H) lung, and (I) MLN. Total number of CD107a+CD8+ T cells from (J) BAL and (K) lung. Data represent mean ± standard deviation. Each group consists of 4–6 mice. Data are representative of at least three independent experiments. *P<0.05, **P<0.01, ***P<0.005.