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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: J Immunol. 2014 May 16;192(12):5776–5788. doi: 10.4049/jimmunol.1301661

FIGURE 2.

FIGURE 2

DCs loaded with anti-hDectin-1-HA1 activate memory Th17, but cannot efficiently induce HA1-specific Th17. (A and C) FACS-sorted naïve and memory CD4+ T cells were co-cultured for 7 days with anti-hDectin-1-HA1-loaded IFNDCs (A) or blood mDCs (C). T cells were restimulated for 48h in the presence or absence of indicated peptides (1 μM). Pep 5 was used as a control peptide. Cytokines in the supernatants were assessed. Error bars indicate mean±SD of triplicate assay. (B and D) Summarized data generated with IFNDCs (B) and blood mDCs (D) from healthy donors. Background values acquired with pep 5 were subtracted. P values were acquired by the Student’s t-test. Indications of donors and peptides tested in (B and D) are summarized in the table.