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Vesicular stomatitis virus (VSV) therapy in the B16 tumor model. C57Bl/6 mice (n = 11–26) were injected subcutaneously with B16 cells and infected locally at the tumor site with 5.0 × 108 PFU of WT or mutant VSV on day 7, 9, and 11. Survival (tumors < 1.7 cm in any diameter) is shown. Data show three combined independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.
