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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Nat Rev Gastroenterol Hepatol. 2013 Jun 25;10(8):473–486. doi: 10.1038/nrgastro.2013.105

Figure 4.

Figure 4

The 5-HT4 receptor is expressed by virtually all epithelial cells, including EC cells, in the murine colon11. This is a photomicrograph from a section of the distal colon of a 5-HT4R(BAC)-eGFP mouse in which cells that express the 5-HT4 receptor fluoresce green. Green fluorescence is present in all of the epithelial cells, as well as a layer of cells in the muscularis mucosa, and in a myenteric ganglion (block arrow). This section was also processed for 5-HT-immunoreactivity to label EC cells, shown in red (arrows).