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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Biochem Pharmacol. 2013 Jul 4;86(5):656–665. doi: 10.1016/j.bcp.2013.06.025

Figure 1.

Figure 1

Nicotine (NIC) stimulates fractional [3H]NE release (top) and total [3H]NE overflow (bottom) from superfused rat hypothalamic slices in a time-and concentration-dependent manner. Arrow indicates the time point at which NIC was added to the superfusion buffer. Data are expressed as mean ± S.E.M. Fractional release data are expressed as a percentage of basal. Basal fractional [3H]NE release was 0.83 ± 0.098% tissue-[3H]. n = 5 rats; ***p < 0.001, different from control (0 NIC; buffer only condition).