Table 1.

Mitral valve biology versus mitral valve hemodynamics in severe mitral regurgitation.

Overall biology	Myxomatous mitral valve disease secondary to chondrocyte phenotype
Mechanism	Ruptured mitral chords	Intact mitral chords	Ruptured mitral chords
Hemodynamics	Small left atrial volume Increase pulmonary pressures	Large left atrial volume Normal pulmonary pressure	Large left atrial volume Normal pulmonary pressure
Long-term outcome	Similar to acute MR	Equal	Equal

MR: Mitral regurgitation.

Data taken from [15].