Figure 6.
Silencing NF-κB p105 reduces cell growth and colony formation of the transformed cells. A, the silencing effect of p105 miRNA in the transformed cells was confirmed by Western blotting. B, cell proliferation was determined for the transformed cells transfected with a control miRNA or p105 (p50) miRNA. C, silencing p105 reduces anchorage-independent growth of the transformed cells. Right, note the reduced number and size of the transformed cells transfected with p105 miRNA. D, quantification of C.