Table 2.
Distribution of Inflammatory Biomarkers and Association Between Each Biomarker and Age, Sex, and Body–Mass Index
| Variable | Geometric mean (geometric 25th, 75th percentile) | Ratioa per 10-y increase in age (95% CI) | Ratiob for sex: male vs. female (95% CI) | Ratioc per 5-unit increase in BMI (95% CI) |
|---|---|---|---|---|
| CRP (mg/L) | 1.75 (0.72, 4.03) | 1.25 (1.04–1.50) | 0.45 (0.34–0.59) | 1.67 (1.42–1.95) |
| IL-1β (pg/mL) | 0.77 (0.11, 2.58) | 1.11 (0.85–1.46) | 0.80 (0.53–1.21) | 0.96 (0.76–1.22) |
| IL-6 (pg/mL) | 3.62 (1.50, 12.0) | 1.39 (1.06–1.83) | 0.63 (0.42–0.95) | 1.19 (0.94–1.50) |
| IL-8 (pg/mL) | 2.24 (1.44, 3.47) | 1.17 (1.04–1.33) | 0.91 (0.75–1.10) | 0.97 (0.87–1.08) |
| TNF-α (pg/mL) | 5.77 (3.38, 11.6) | 1.22 (1.05–1.43) | 0.91 (0.72–1.15) | 1.03 (0.90–1.18) |
| sTNFRI (pg/mL) | 1430 (1186, 1732) | 1.12 (1.06–1.19) | 1.09 (1.00–1.20) | 1.05 (1.00–1.11) |
| sTNFRII (pg/mL) | 5677 (4768, 6683) | 1.17 (1.11–1.23) | 1.04 (0.97–1.12) | 1.06 (1.02–1.11) |
| PGE-M (ng/mg creatinine) | 5.43 (3.38, 8.55) | 1.16 (1.04–1.30) | 1.20 (1.01–1.42) | 1.04 (0.94–1.16) |
a
Adjusted for sex and BMI (continuous).
b
Adjusted for age (continuous) and BMI (continuous).
c
Adjusted for age (continuous) and sex.
BMI, body mass index; PGE-M, prostaglandin E2 metabolite.