. Author manuscript; available in PMC: 2014 Jun 9.

Published in final edited form as: Clin Cancer Res. 2011 Apr 28;17(12):4091–4100. doi: 10.1158/1078-0432.CCR-10-2579

Table 3.

Radiation dose estimates (mGy/mCi) stratified by antibody dose

	Total antibody administered
	100 mg (n = 15)^a	<10 mg (n = 5)
Whole body	2.7 ± 0.4	2.5 ± 0.4
Red marrow	4.1 ± 1.2	3.8 ± 0.9
Liver	15.0 ± 5.0	20.8 ± 1.9
Spleen	20.6 ± 12.9	22 ± 13.8
Lungs	14.8 ± 5.7	11.7 ± 4.6
Kidneys	16.0 ± 5.0	18.7 ± 4.8
Testes^b	6.9 ± 5.2	8.2 ± 3.3
Ovaries^c	2.1 ± 0.2	1.9 ± 0.3
Lens of eye	2.0 ± 0.2	1.6 ± 0.4
Urinary bladder	1.4 ± 0.4	1.7 ± 0.3

NOTE: Mean ± SD of the estimated radiation dose to whole body and organs from ⁹⁰Y-hPAM4 per mCi of ⁹⁰Y administrated.

Patients receiving additional hPAM4 with both ¹¹¹In-hPAM4 and ⁹⁰Y-hPAM4.

Calculated in males only.

Calculated in females only.