Table 2.
Odds ratios for Prothrombin G20210A and ischemic stroke in young-adults of European Ancestry as stratified by risk factors.
| No. FII/No. of Cases | No. FII/No. of Controls | OR (basic model) | 95%CI | P value (*basic model) | P value (ψfull model) | ||
|---|---|---|---|---|---|---|---|
| Entire Population | 14/397 | 6/426 | 2.5 | 0.9 - 6.5 | 0.07 | 0.07 | |
| Gender | Male | 11/249 | 4/236 | 2.8 | 0.9 - 8.9 | 0.09 | 0.09 |
| Female | 3/148 | 2/190 | 1.9 | 0.3 - 11.8 | 0.47 | 0.47 | |
| OC use | Yes | 1/34 | 0/20 | NE | NE | NE | NE |
| No | 2/114 | 2/170 | 1.7 | 0.2 - 12.0 | 0.62 | 0.45 | |
| Current Smoking | Yes | 4/169 | 1/103 | 2.2 | 0.2 - 20.3 | 0.49 | 0.38 |
| No | 10/228 | 5/323 | 3.0 | 1.0 - 8.8 | 0.05 | 0.12 | |
| Migraine with Auraξ | Yes | 3/105 | 0/86 | NE | NE | NE | NE |
| No | 10/287 | 6/340 | 2.0 | 0.7 - 5.5 | 0.20 | 0.24 | |
| Age | <42 | 8/167 | 2/235 | 5.9 | 1.2 - 28.1 | 0.03 | 0.03 |
| ≥42 | 6/230 | 4/191 | 1.4 | 0.4 - 5.1 | 0.63 | 0.94 |
*
Includes: age and gender.
ψ
Includes: age, gender, hypertension, diabetes, previous myocardial infraction, current oral contraceptive use, current smoking, migraine with aura. NE = not estimable
ξ
Five case subjects did not have migraine information available.