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Embedded Alu RNAs can be alternatively spliced. A) Schematic of the potential splice sites in the sense and antisense Alu sequence (62). Arrows above the Alu elements indicate potential 5’ splice sites, arrows below the Alu elements indicate potential 3’ splice sites. B) Schematic illustrating exonization of an embedded antisense Alu RNA. Sequences within Alu RNA are recognized as splice sites, resulting in a mature mRNA isoform containing a portion of the Alu sequence.
