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Global first-order degradation rate constants at 323 K for each degradation pathway (aggregation, deamidation and oxidation) for rhGH on the surface and within the bulk solid of all the formulations.
| Degradation Route |
ksg,i (% per week) |
kbg,i (% per week) |
|---|---|---|
| i = Aggregation | 11.6 | 0 (<10−3) |
| i =Deamidation | 35.7 | 0.5 |
| i =Oxidation | 90.8 | 0.7 |
