Table 1.
Cases | Controls | ||
---|---|---|---|
n= 687 (%) |
n= 907 (%) |
p valueb | |
Age (years)c | 52.1 (9.8) | 51.1 (9.2) | 0.053 |
Breast cancer in first degree relatives | |||
No | 92.7 | 96.1 | 0.003 |
Yes | 7.3 | 3.9 | |
Daily caloric intake (kcal)c | 2170.8 (852.6) | 1832.1 (708.0) | < 0.001 |
Daily caloric intake (kcal) | |||
< 1596.0 | 24.8 | 41.4 | < 0.001 |
1596.0 – 2192.9 | 32.8 | 33.6 | |
> 2192.9 | 42.4 | 25.0 | |
Occasional intake of > 1 alcohol drinks within a month over a period of ≥ 1 yearsd |
|||
No | 80.3 | 90.0 | < 0.001 |
Yes | 19.7 | 10.0 | |
Weekly moderate-intensity physical activity (hours)c |
9.7 (12.3) | 15.3 (16.2) | < 0.001 |
Body Mass Index (kg/m2)c | 29.4 (5.6) | 30.6 (5.4) | < 0.001 |
Tobacco smoking, once during life | |||
No | 73.1 | 79.5 | 0.003 |
Yes | 26.9 | 20.5 | |
Tobacco smoking ≥ 100 cigarettes during lifetimee | |||
No | 73.1 | 79.5 | 0.003 |
Yes | 26.9 | 20.5 | |
Socio-economic status | |||
Low | 30.8 | 35.0 | < 0.001 |
Middle | 24.5 | 32.0 | |
High | 44.7 | 33.0 | |
Menopausal status | |||
Premenopause | 42.9 | 45.0 | 0.416 |
Postmenopause | 57.1 | 55.0 | |
Oral contraceptives use, once during lifetime | |||
No | 52.8 | 54.2 | 0.577 |
Yes | 47.2 | 45.8 | |
Age at menarche (years)c | 12.8 (1.7) | 12.9 (1.6) | 0.169 |
Age at first live birth (years)c | 20.8 (8.4) | 20.2 (6.5) | 0.001 |
Parityc | 3.0 (2.2) | 3.8 (2.5) | < 0.001 |
Lactation (months)c | 21.6 (28.3) | 31.0 (35.9) | < 0.001 |
Self-report of diabetes mellitus | |||
No | 79.2 | 84.3 | 0.008 |
Yes | 20.8 | 15.7 | |
Self-report of arterial hypertension | |||
No | 62.1 | 67.0 | 0.075 |
Yes | 35.1 | 31.3 | |
Personal history of benign breast cancer | |||
No | 85.1 | 93.0 | < 0.001 |
Yes | 14.9 | 7.0 | |
Ancestryc | |||
Native | 0.60 (0.21) | 0.64 (0.20) | < 0.001 |
European | 0.36 (0.20) | 0.32 (0.18) | < 0.001 |
African | 0.04 (0.06) | 0.04 (0.05) | 0.248 |
rs2981582 (C>T) | |||
CC | 33.9 | 38.9 | 0.007 |
CT | 45.0 | 45.8 | |
TT | 21.1 | 15.3 | |
Allelic frequencies | |||
C | 56.4 | 61.8 | 0.002 |
T | 43.6 | 38.2 |
Due to missing values, percentages may not total 100%.
Relative frequency is shown (%) unless otherwise specified.
P-vaue.
Arithmetic mean (standard deviation).
Among women reporting having consumed alcohol sometime during their lifetime.
Among women reporting having smoked tobacco sometime during their lifetime.
Percentages do not reach 100% due to missing values