Figure 1.

The effect of NO-711 (30 μM) (A) and β-alanine (100 μM) (B) on [³H]GABA uptake by cortical synaptosomes. [³H]GABA uptake: 1) control; 2) acute effects of the inhibitors, ie, NO-711 (A) or β-alanine (B) and [³H]GABA when they are simultaneously added to the medium; 3) preliminary incubation of synaptosomes with NO-711 (A) or β-alanine (B) for 15 minutes. Data are presented as mean ± standard error of the mean of three independent experiments, each performed with different synaptosomal preparations in triplicate.