Table 1.
Source | PrPSc concentration in tissues (g g−1) and fluids (g ml−1) |
---|---|
Brain | 2.3 × 10−5 ± 6.8 × 10−6 |
Spleen | 2.0 × 10−11 ± 1.1 × 10−11 |
Buffy coat | 2.6 × 10−13 ± 2.4 × 10−13 |
Plasma | 1.3 × 10−14 ± 1.1 × 10−14 |
Urine | 2.0 × 10−16 ± 1.7 × 10−16 |
PrPSc concentration in tissues and fluids was estimated by determining the number of PMCA rounds required to detect the signal by western blots and obtaining the concentration from the standard curve. Indicated values are means ± s.e.m. for five hamsters.