Skip to main content
. Author manuscript; available in PMC: 2014 Jun 9.
Published in final edited form as: Radiat Res. 2011 Feb 14;175(5):561–568. doi: 10.1667/RR2453.1

FIG. 3.

FIG. 3

The rescue effect of NO can be blocked using the NO scavenger PTIO. Data were collected 72 and 96 h after γ irradiation. The effects of SNP shown at each time are consistent with the concept that NO donors can be used to rescue satellite cell proliferation after irradiation. However, to provide further evidence of the importance of NO, we used the NO scavenger PTIO to blunt/block the rescue effect of SNP. At each time and each dose of γ radiation, PTIO was highly effective in blocking the rescue effect of SNP. A PTIO-only treated group was also included at each time as a negative control, and the mean value was only 2% greater than the control cell counts (data not shown). All results are reported as means ± SE. Data for each time and each dose of γ radiation were analyzed using two-way ANOVA. The interaction effect (SNP × PTIO main effect) was highly significant (P = 5 0.001) at each dose and time.