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. Author manuscript; available in PMC: 2014 Jun 9.
Published in final edited form as: Gynecol Oncol. 2006 Oct 30;104(2):470–479. doi: 10.1016/j.ygyno.2006.08.048

Fig. 4.

Fig. 4

Inhibition of PI3K, PAI-1 and uPA alter SKOV-3 wound-induced migration. (A) Wound-induced migration in the presence of increasing doses of LY294002 or wortmannin was measured for 12 h. *p<0.05, **p<0.01 compared with untreated SKOV-3 cells. (B) Wound-induced migration in the presence of 25 µM LY294002 and uPA- and PAI-1-blocking antibodies (each at 20 µg/ml) for 12 h. The graphs represent the average of 2–4 separate experiments performed in triplicate. *p<0.05, **p<0.01 compared with SKOV-3 cells treated with 25 µM LY294002.