Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Metabolic oligosaccharide engineering can be employed to covalently deliver therapeutics or diagnostics to bacterial glycans. First, bacterial cells metabolically process an unnatural sugar that contains a bioorthogonal chemical reporter (X) into cellular glycans. In a second step, the chemical reporter undergoes covalent elaboration with a reactive partner (Y) conjugated to a therapeutic or diagnostic to fo6rm a covalent adduct.
