Table 2.

Multicomponent catalytic reactions with α-alkenylaluminum reagents.^[a]

Entry		ECA conv. [%][b]	Prod.	Carbomet./acyl. yield [%];[c] ECA yield [%][d]	e.r.[e]
1		>98	4a	80; 82	99:1
2		>98	4b	40; 95	97.5:2.5
3		>98	4c	88; 88	99:1
4		88	4d	60; 48	99:1
5		>98	4e	80; 95	98:2
6		>98	4 f	80; 80	97:3
7		>98	4g	80; 97	98:2
8		>98	4h	80; 71	99:1
9		>98	4i	40; 81	98:2
10		>98	4j	63; 95	99:1
11		>98	4k	62; 87	95:5
12		>98	4l	80; 85	97.5:2.5
13		>98	4m	61; 83	92:8

^[a]Reactions were performed under N₂ atmosphere; enones generated with >98% E selectivity in all cases.

^[b]Determined by analysis of 400 MHz ¹H NMR spectra of unpurified mixtures (±2%).

^[c]Yield of isolated and purified products (±5%).

^[d]Determined by HPLC analysis; see the Supporting Information for details.

^[e]NHC-Ag complex 1a was used as catalyst precursor.

TBS = tert-butyl-(dimethyl)silyl.