Figure 2. Effect of sodium selenite on glutathione peroxidase activity.
DU-145, PC-3 and LNCaP prostate cancer cells were treated with various concentrations of sodium selenite for 5 days at the indicated concentrations. The graph represents the activity of glutathione peroxidase as measured by the amount of reduced NADPH produced/min/mg of total protein/sample. Note that the level of glutathione peroxidase activity remains low in DU-145 and LNCaP cells as compared to the level in PC-3 cells.